DNA Reports
Disease Risks
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Disease Risks

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Practicing preventive health through early screening

Screen for 115+ diseases that may affect you through your lifetime, and learn what you can do to mitigate any genetic risks.
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Assess your risk for 115+ serious diseasesGet a detailed assessment of your genetic disease risk to make informed decisions about your lifestyle habits.
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Learn more about diseases you may have a high risk forExplore expert explanations for each disease – education is always the first step to prevention.
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65Health Conditions
Cardiovascular Disorders
  • Abdominal Aortic Aneurysm
  • Atrial Fibrillation
  • Early Onset Myocardial Infarction
  • Dilated Cardiomyopathy (DCM)
  • Thoracic Aortic Aneurysm and Dissection
  • Hypertrophic Cardiomyopathy (HCM)
  • Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
  • Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
  • Long QT Syndrome
  • Brugada Syndrome
  • Orthostatic Hypotension
  • Peripheral Artery Disease
  • Short QT Syndrome
Neurological and Mental Health Disorders
  • Anxiety Disorder
  • Attention Deficit Hyperactivity Disorder (ADHD)
  • Autism
  • Cluster Headache
  • Major Depression
  • Migraine
  • Opioid Addiction
Respiratory and Allergic Conditions
  • Allergic Rhinitis
  • Allergies
  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Idiopathic Pulmonary Fibrosis (IPF)
  • Influenza (Flu) Susceptibility
Autoimmune and Inflammatory Disorders
  • Alopecia Areata
  • Ankylosing Spondylitis
  • Crohn's Disease
  • Inflammatory Skin Disease
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Childhood Ear Infection
  • Chronic Periodontitis
  • Gout
  • Selective IgA deficiency
  • Ulcerative Colitis
Metabolic and Endocrine Disorders
  • Hyperhomocysteinemia
  • Hypertriglyceridemia
  • Hypothyroidism
  • Insulin Resistance and Response
  • Polycystic Ovary Syndrome
  • High-Density Lipoprotein (HDL) Cholesterol
  • Sitosterolemia
Musculoskeletal Disorders
  • Lumbar Degenerative Disc Disease
  • Osteoarthritis
  • Temporomandibular Joint Disorder
  • Osteoporosis
Dermatological Disorders
  • Vitiligo
  • Psoriasis
  • Atopic Dermatitis
Genetic and Syndromic Disorders
  • Noonan Syndrome
  • Syndromic Hearing Loss
Reproductive Disorders
  • Endometriosis
  • Male Infertility
Other Medical Conditions
  • Deep Vein Thrombosis
  • Gallstone Disease
  • Kidney Stones
  • Age-Related Macular Degeneration (AMD)
  • Androgenetic Alopecia
  • Glaucoma
  • Tooth Decay
  • Non-Syndromic Hearing Loss
  • Irritable Bowel Syndrome (IBS)
  • Duodenal Ulcer
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Valuable insights for each report

Generated with 99.9% accuracyClick into each result on your Disease Risk report to learn more about what it means, how we tested for it, and what you can do next.
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Get personalised health advice from experts

Make your DNA results work for you

All reports include tips from our genetic and health professionals, so you can understand how to apply your DNA insights to your daily lifestyle habits and make changes to improve your health.

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Ready to learn more about the World’s Most Comprehensive DNA Test?

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Our Best-Selling DNA TestCircleDNA Premium

Get 500+ reports that help you understand:

  • Your risk level of inherited cancers & disease
  • Insights about your optimal diet, fitness, and wellness
  • Carrier conditions that may affect your future family
  • Prescription drugs response
  • Ancestry breakdown

Convenient at-home saliva collection with free pick-up

Complimentary 30-minute genetic consultation included

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Don’t just take our word for it, see what our Circle Changemakers have to say

Got questions? Get answers

Check out our frequently asked questions below, or contact us for more information.
What is CircleDNA?
CircleDNA is the world’s most comprehensive DNA test that enables you to take full control of your health by understanding your genetic blueprint, so you can make informed decisions about your health with full confidence. This at-home test provides 500+ reports about your diet, nutrition, sports, cancer and disease risks, carrier conditions and much more with a simple saliva swab. The results are delivered within 18 business days in an easy-to-use mobile app.
Can disease risk reports tell me how to treat these conditions?
Genetic testing is used to assess an individual's lifetime risk of developing certain conditions. However, it's important to understand that these reports are not diagnostic and cannot provide specific treatment recommendations for identified conditions. Instead, disease risk reports focus on estimating an individual's predisposition to certain diseases based on their genetic profile. They may offer information about preventive measures or screening recommendations to detect diseases early or reduce the risk of developing them.It's crucial to recognize that genetic risk factors are just one part of the equation. Other factors such as lifestyle choices, environmental exposures, and personal medical history also significantly contribute to disease development and progression. To determine the most appropriate treatment for a specific condition, consulting with a healthcare professional is essential.
Can disease risk reports help me plan for my family's health too?
All conditions in the Disease Risk panel are complex conditions caused by the interaction of multiple genetic variants, each contributing a small effect to the overall risk. It is important to understand that each family member has a unique genetic profile, as well as variations in lifestyle and environmental factors. Therefore, disease risk reports for complex conditions cannot be automatically applied to the entire family. Personalized risk assessments and interpretations are necessary on an individual basis.However, our Disease Risk reports also consider single mutations that significantly increase the risk of certain diseases. These mutations can be inherited or shared among family members. Our reports can identify these mutations and provide insights into the potential risk of developing specific diseases within your family.
How are my data and privacy protected?
CircleDNA adheres to the leading international security standard, ISO-27001, as we implement physical, technical, and administrative measures to prevent any unauthorized access to, or disclosure of, your sensitive information. All connections are encrypted with Secure Socket Layer (SSL) technology. We do not sell, lease, or rent your personal information to any third party without your explicit consent. Your data will also never be shared with anyone outside of CircleDNA for marketing or other purposes. You are the only individual or party who is able to authorize how your information is used, stored, and shared with others.